RPL13A antibody , Cat. # FNab07413

SKU: FNab07413

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT(gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs(such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.

Immunogen:ribosomal protein L13a

Synonyms:

Observed MW:25-28 kDa

Uniprot ID:P40429

Reactivity:Human, Mouse

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:23521

Research Area:Metabolism