RFX6 Rabbit Polyclonal Antibody

SKU: BT-AP04450

Size:100μL

Background:The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin| but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function| thus| restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome| which is characterized by neonatal diabetes with pancreatic hypoplasia| duodenal and jejunal atresia| and gall bladder agenesis.

Research_area:Epigenetics and nuclear signaling

Target_protein:RFX6

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RFX6

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):102080

UniProt accession:Human: Q8HWS3; Mouse: Q8C7R7

Synonyms:RFX6

GeneID:Human: 222546; Mouse: 320995