RFA1 Rabbit Polyclonal Antibody

SKU: BT-AP12274

Size:100μL

Background:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.|PTM:Phosphorylated upon DNA damage| probably by ATM or ATR.|Belongs to the replication factor A protein 1 family.|subunit:Heterotrimer of 70| 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.|

Research_area:Epigenetics and nuclear signaling

Target_protein:RPA1

applications:WB, ELISA

Reactivity:Human, Monkey, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RFA1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):67760

UniProt accession:Human: P27694; Mouse: Q8VEE4

Synonyms:RFA1; Replication protein A 70 kDa DNA-binding subunit; RP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding protein

GeneID:Human: 6117; Mouse: 68275