Recombinant Vimentin/VIM Monoclonal Antibody

SKU: AN300103P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:VIM

Target Synonym:HEL;Epididymis luminal protein;CTRCT;CTRCT30;HEL113;Vimentin;VIM;Epididymis luminal protein 113;VIME;FLJ36605;epididymis secretory sperm binding protein;CTRCT30;HEL113;vimentin;CTRCT30;Epididymis luminal protein 113;FLJ36605;HEL113;VIM;VIME;Vimentin

Research Areas:Neuroscience;Signal Transduction;Stem Cells;Cancer;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:11G7

UNIProt ID:P08670

Accession:

Background:Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. Therefore, in general, it is accepted that vimentin is the cytoskeletal component responsible for maintaining cell integrity. Vimentin is also responsible for stabilizing cytoskeletal interactions. It is found that vimentin control the transport of low-density lipoprotein. It has been used as a sarcoma tumor marker to identify mesenchyme.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the center region of the Human Vimentin/VIM

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;IHC-P 1:1000-1:10000;

Calculated MW:54 kDa

ObservedMW:55 kDa