Recombinant TXNIP Monoclonal Antibody

SKU: AN301188L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:TXNIP

Target Synonym:VDUP;Thioredoxin-binding protein;Vitamin D3-Upregulated Protein;Vitamin D3 up-regulated protein;ARRDC;HHCPA;TXNIP;ARRDC6;EST01027;HHCPA78;THIF;VDUP1;Thioredoxin Interacting Protein;Vitamin D3-Upregulated Protein 1;Thioredoxin-interacting protein;Thioredoxin-binding protein 2;Vitamin D3 up-regulated protein 1;TXNIP

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9D14

UNIProt ID:Q9H3M7

Accession:

Background:This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human TXNIP protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:1000-1:5000

Calculated MW:44 kDa

ObservedMW:55 kDa