Recombinant SUV39H2 Monoclonal Antibody

SKU: AN301817L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:SUV39H2

Target Synonym:SUV39H;SUV39H2;KMT1B;FLJ23414;H3 K9 HMTase 2;H3-K9-HMTase 2;Histone H3 K9 methyltransferase 2;Histone H3-K9 methyltransferase 2;Histone lysine N methyltransferase H3 lysine 9 specific 2;Histone lysine N methyltransferase SUV39H2;Histone-lysine N-methyltransferase SUV39H2;Lysine N methyltransferase 1B;Lysine N-methyltransferase 1B;sSuppressor of variegation 3 9 homolog 2 (Drosophila);Su(var)3 9 Drosophila homolog of 2;Su(var)3 9 homolog 2;Su(var)3-9 homolog 2;Suppressor of variegation 3 9 homolog 2;Suppressor of variegation 3-9 homolog 2;SUV92

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A529

UNIProt ID:Q9H5I1

Accession:

Background:SUV39H2, also known as KMT1B, is a member of the SUV39 subfamily of lysine methyltransferases (KMTs) that plays a significant role in histone H3-K9 di-/Trimethylation, transcriptional regulation and cell cycle. Overexpressions of SUV39H2 at gene, mRNA and protein levels are known to be associated with a range of cancers: leukemia, lymphomas, lung cancer, breast cancer, colorectal cancer, gastric cancer, hepatocellular cancer and so on. Accumulating evidence indicates that SUV39H2 acts as an oncogene and contributes to the initiation and progression of cancers.

Concentration:1 mg/mL

Immunogen:Recombinant human SUV39H2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:47 kDa

ObservedMW:47, 50 kDa