Recombinant SETD1A Monoclonal Antibody

SKU: AN301557L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:SETD1A

Target Synonym:Set;KIAA;Set1;KMT2F;Set1A;SETD1A;KIAA0339;Histone-lysine N-methyltransferase SETD1A;hSET1A;KMT2F;Lysine N methyltransferase 2F;Lysine N-methyltransferase 2F;SET domain containing 1A;SET domain containing protein 1A;SET domain-containing protein 1A;SET1;Set1 Ash2 histone methyltransferase complex subunit SET1;Set1/Ash2 histone methyltransferase complex subunit SET1;SET1A

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:IHC;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A256

UNIProt ID:O15047

Accession:

Background:hSET1 is a component of the histone methyltransferase (HMT) complex, which is a member of the COMPASS family, has H3K4 methyltransferase activity, and is closely related to development and tumors. hSET1 can produce mono-, di- and Trimethylation at lys4 (K4) on histone H3. This activity is blocked by the pre-methylation of the transcription repressor K9, indicating that the SET1/ASH2 complex can cause crosstalk between K9 methylation and K4 methylation. SET1 protein may play a role in synaptic function and neuron development. In addition, hSET1 protein can affect the proliferation and apoptosis of leukemia cells, and promote differentiation into neutrophils, providing new ideas for the treatment of leukemia and other cancers.

Concentration:1 mg/mL

Immunogen:Recombinant human SETD1A fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:50-1:100;IF 1:100-1:500;FCM 1:50-1:100

Calculated MW:

ObservedMW: