Recombinant Rat MEC/CCL28protein

SKU: CD00090

Size:5 ug

Background:CCL28 belongs to CC family chemokine, also named mucosae-associated epithelial chemokine (MEC). The CCL28 mRNA is highly expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. The protein signals through CCR3 and CCR10, and chemotactic for resting CD4, CD8 T-cells and eosinophils. CCL28 shares the most homology with CCL27/CTACK.

Research_area:Immunology

Purity:> 96 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Rat Mucosae-associated Epithelial Chemokine/CCL28

Biological activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 5.-5 ng/ml.

Synonyms:MEC/CCL28, Scya28,Rat

Endotoxin:Less than 1 EU/μg of rRtMEC/CCL28 as determined by LAL method.

Storage:-20ºC

Sequence:SEAILPIASS CCTEVSHHIP RRLLERVNSC SIQRADGDCD LAAVILHVKR RRICVSPHNP TLKRWMSASE MKNGKENLCP RKKQDSGKDR KGHTPRKHGK HGTRRIHGTH DHEAPR

uniprot accession:Q91Y39

Molecular weight:Approximately 13.1 kDa, a single non-glycosylated polypeptide chain containing 116 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 mM PB, pH 7.4, 2 mM NaCl.