Recombinant Rat IL-4 Protein

SKU: PDMR100003

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:IL-4

Target Synonym:Interleukin;B-cell growth factor;B-cell stimulatory factor;Lymphocyte stimulatory factor;BCGF1;B-cell IGG differentiation factor;B-cell stimulatory factor 1;BCGF-1;Binetrakin;BSF1;Interleukin-4;Lymphocyte stimulatory factor 1;Pitrakinra;Il4;BSF-1;Lymphocy;Il 4;B-cell growth factor 1;Il-4;IL4、BCGF-1、BCGF1、BSF-1、BSF1

Research Areas:Cancer;Cardiovascular;Immunology;

Conjugation:

Target Species:Rat

Expression Host:HEK293 Cells

Application:

Fusion tag:C-His

UNIProt ID:P20096

Accession:P20096

Background:Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Ser147

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% Tween 80.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:16.5 kDa

ObservedMW:17 kDa