Recombinant Rat CCL2/JE/MCP-1 Protein(Trx Tag)

SKU: PDER100141

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:CCL2/JE/MCP-1

Target Synonym:CCL;Scya;C-C motif chemokine;Small-inducible cytokine A;Monocyte chemotactic protein;Monocyte chemoattractant protein;GDCF;HSMCR;GDCF-2;HC11;HSMCR30;MCAF;MCP-1;Monocyte chemotactic protein 1;SMC-CF;Ccl2;C-C motif chemokine 2;Small-inducible cytokine A2;Monocyte chemotactic protein 1 (MCP-1);Monocyte chemoattractant protein 1;Immediate-early serum-responsive protein JE;Je;Mcp1;Scya2

Research Areas:

Conjugation:

Target Species:Rat

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:P14844

Accession:P14844

Background:Monocyte chemoattractant protein 1 (CCL2/JE/MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. CCL2/JE/MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of CCL2/JE/MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.

Concentration:

Activity:Not validated for activity

Sequence:Gln24-Asn148

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:33.64 kDa

ObservedMW:30 kDa