Recombinant PYK2 Monoclonal Antibody

SKU: AN300636L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PYK2

Target Synonym:FAK;PYK;FADK;PTK2B;CADTK;CAKB;FADK2;FAK2;PKB;PTK;PYK2;RAFTK;CAKbeta;CAK-beta;Calcium regulated non receptor proline rich tyrosine kinase;Calcium-dependent tyrosine kinase;Cell adhesion kinase beta;E430023O05Rik;EC 2.7.10.2;FADK 2;Focal adhesion kinase 2;MGC124628;Proline-rich tyrosine kinase 2;Protein kinase B;Protein Tyrosine Kinase 2 Beta;Protein-tyrosine kinase 2-beta;PTK2B protein tyrosine kinase 2 beta;RAFTK2;Related adhesion focal tyrosine kinase

Research Areas:Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:7F11

UNIProt ID:Q14289

Accession:

Background:This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human PYK2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:116 kDa

ObservedMW:116 kDa