Recombinant Pig Protocadherin beta 7 (PCDHB7), partial

SKU: A0A287BG69

Size: 100ug. Other sizes are also available.

Activity: Not tested

Research Areas: Neuroscience

Uniprot ID: A0A287BG69

Gene Names: PCDHB7

Alternative Name(s):

Abbreviation: Recombinant Pig PCDHB7 protein, partial

Organism: Sus scrofa (Pig)

Source: E.coli

Expression Region: 21-684aa

Protein Length: Partial

Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged

Target Protein Sequence: GAEPLRYFVEEETERGTFLANLANDLGLGVGELSARAPRIGSDQNIRFLLLNPLTGDLLLNEKLDREELCGPAEPCVLPFQLLLEEPLEIFRAELWVRDINDNSPVFLHREILLKILESTTAGAAFLLESAQDSDAGTNSLRNYTIGPNDYFHITVHDGEEGILYPELVMDRALDREQVPELSLTLTALDGGSPPRSGTALVHIQVLDVNDNAPEFVQSLYKVQVPENSPVGSVVVTVSARDLDAGSNGEIVYAFLYATERILETFQINPASGSLYLKAELNYEAVQTYTLIIQAKDGGGLSGKCTVVVEVTDINDNPPELVMSSLTSSIKENSPETVVAVFRIRDRDSGNNAKMVCSIQAHLPFVLKPSVENYYTLVTERPLDRESQAEYNITISVSDLGTPRRHTQHNLTVRVADVNDNAPAFSQPAYTLRVRENNSPALHIGTVRATDADAGANAQLTYSLLPPSDPHLPLASLVAINPDTGQLFALRALDYEALRAFDFQVRAADRGAPALSSQARVRVLVADANDHAPVVLYPPPNASAPCTELLPRAAEPGYLLAKVVAVDGDAGQNAWLSYRLLQATEPGLFGVGAHSGEVRTARPLSERDAPRQRLLLLVRDHGEPPLSASVPLHVLLVDGFSQPYLPPPEAPGRAPGAGAGADEP

MW: 79.3 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Endotoxin: Not test

Biological_Activity:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Relevance: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV: ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation.

Reference:

Function: