Recombinant Phospho-Tau (Thr217) Monoclonal Antibody

SKU: AN300377L

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:MAPT

Target Synonym:FTDP;PPP1R;DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;TAU;MAPT;Microtubule-Associated Protein Tau;Neurofibrillary Tangle Protein;Paired Helical Filament-Tau;PHF-Tau;pMAPT/pTAU;TAU and MAPT;N/A;AI413597;AW045860;FLJ31424;FTDP 17;G protein beta1/gamma2 subunit interacting factor 1;included;MGC134287;MGC138549;MGC156663;Microtubule associated protein tau;Microtubule associated protein tau isoform 4;Mtapt;Paired helical filament tau;PHF tau;Protein phosphatase 1;pTau;regulatory subunit 103;RNPTAU;Tauopathy and respiratory failure

Research Areas:Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Monoclonal

Clone NO.:6H8

UNIProt ID:P10636

Accession:

Background:This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau

Buffer:10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:46 kDa

ObservedMW:50-70 kDa