Recombinant Phospho-CrkL (Tyr207) Monoclonal Antibody

SKU: AN300157L

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:CRKL

Target Synonym:HGNC;CRKL;Crk L;Crk like protein;Crk-like protein;Crkol;HGNC:2363;Oncogene CrkL;V crk avian sarcoma virus CT10 oncogene homolog like;v crk sarcoma virus CT10 oncogene homolog (avian) like;V crk sarcoma virus CT10 oncogene homolog avian like;HGNC:2363

Research Areas:Neuroscience;Epigenetics and Nuclear Signaling;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:5B9

UNIProt ID:P46109

Accession:

Background:This gene encodes a protein kinase containing SH2 and SH0 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the residues around (Tyr207) of Human Phospho-CrkL

Buffer:10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Purification method:Protein A

Dilution:WB 1:1000-1:5000;

Calculated MW:35 kDa

ObservedMW:38 kDa