Recombinant Phospho-CD31 (Tyr713) Monoclonal Antibody

SKU: AN302093L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Phospho-CD31 (Tyr713)

Target Synonym:PECA;cluster of differentiation;PECAM1;CD31;CD31/EndoCAM;GPIIA;PECA1;PECAM-1;endoCAM;cluster of differentiation 31;Platelet endothelial cell adhesion molecule;endocam;Adhesion molecule;CD31 antigen;CD31 EndoCAM;FLJ34100;FLJ58394;GPIIA';PECAM;Pecam 1;PECAM 1 CD31 EndoCAM;PECAM1;Platelet and endothelial cell adhesion molecule 1;Platelet/endothelial cell adhesion molecule 1;CD31;EndoCAM;GPIIA;PECA1;PECAM-1;Platelet endothelial cell adhesion molecule

Research Areas:Cardiovascular;Signal Transduction;Stem Cells;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A817

UNIProt ID:P16284

Accession:

Background:CD31, also named as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modulates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCγ, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.

Concentration:1 mg/mL

Immunogen:phosphorylated human CD31 (Tyr713) peptide

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:83 kDa

ObservedMW:130 kDa