Recombinant Phospho-c-Myc (Ser62) Monoclonal Antibody

SKU: AN302092L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Phospho-c-Myc (Ser62)

Target Synonym:bHLHe;MYC BHLHE;MRTL;MYCC;bHLHe39;c-Myc;MYC;MYC BHLHE39;AU016757;Avian myelocytomatosis viral oncogene homolog;c Myc;Class E basic helix-loop-helix protein 39;Myc protein;Myc proto oncogene protein;Myc proto-oncogene protein;Myc2;myc-related translation/localization regulatory factor;Myelocytomatosis oncogene;Niard;Nird;Oncogene Myc;OTTHUMP00000158589;Proto-oncogene c-Myc;Protooncogene homologous to myelocytomatosis virus;RNCMYC;Transcription factor p64;Transcriptional regulator Myc-A;V-Myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog (avian);V-myc myelocytomatosis viral oncogene homolog(avian)

Research Areas:Epigenetics and Nuclear Signaling;Stem Cells;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A816

UNIProt ID:P01106

Accession:

Background:Myc, also known as c-Myc, together with l-Myc and n-Myc, belongs to the Myc family of transcription factors. Myc has a basic helix-loop-helix leucine zipper domain and through heterodimerization can bind and regulate the transcriptional activity of genes. It is a key player in the regulation of cell growth and cell cycle progression and acts as a proto-oncogene. Myc localizes to the nucleus but can also be present in the cytoplasm of certain cancer types. Myc is ubiquitously expressed in almost all cell types and its expression positively correlates with tissue proliferative capacity. Myc is also expressed during embryogenesis. Myc is upregulated in many cancer types, especially in aggressive, poorly differentiated tumors. Mutations in the MYC gene and breakpoint translocations within the MYC gene cause Burkitt lymphoma. In addition, Myc is subject to various post-translational modifications, including phosphorylation, acetylation, and ubiquitinylation.

Concentration:1 mg/mL

Immunogen:phosphorylated human c-Myc (Ser62) peptide

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:49 kDa

ObservedMW:55 kDa