Recombinant Phospho-AMPK α1, 2 (Thr183, Thr172) Monoclonal Antibody

SKU: AN301152L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:AMPK α1, 2

Target Synonym:AMPK1;PRKAA1;Tau-protein kinase PRKAA1;HMGCR kinase;ACACA kinase;AMPK subunit alpha-1;AMPKα1/2

Research Areas:Neuroscience;Signal Transduction;Cardiovascular;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11G1

UNIProt ID:Q13131;P54646

Accession:

Background:The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Thr183, Thr172) of Human Phospho-AMPK α1, 2

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:62 kDa,64 kDa

ObservedMW:62 kDa