Recombinant PDK2 Monoclonal Antibody

SKU: AN301725L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:PDK2

Target Synonym:PDK;PDHK;Pyruvate dehydrogenase kinase isoform;Pyruvate dehydrogenase lipoamide kinase isozyme;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme;isozyme;PDK2;PDHK2;PDKII;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2;isozyme 2;mitochondrial;Pyruvate dehydrogenase kinase;Pyruvate dehydrogenase kinase isoform 2;Pyruvate dehydrogenase lipoamide kinase isozyme 2

Research Areas:Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A433

UNIProt ID:Q15119

Accession:

Background:[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability.

Concentration:1 mg/mL

Immunogen:Recombinant human PDK2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:10000

Calculated MW:46 kDa

ObservedMW:46 kDa