Recombinant NQO1 Monoclonal Antibody

SKU: AN300988L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:NQO1

Target Synonym:NQO;DIA;NMOR;DHQU;DIA4;DTD;NMOR1;NMORI;QR1;NQO1;Azoreductase;Cytochrome b 5 reductase;DIA 4;Diaphorase (NADH/NADPH);Diaphorase (NADH/NADPH) (cytochrome b 5 reductase);Diaphorase 4;Dioxin inducible 1;DT diaphorase;DT-diaphorase;Menadione reductase;NAD(P)H dehydrogenase [quinone] 1;NAD(P)H dehydrogenase quinone 1;NAD(P)H menadione oxidoreductase 1 dioxin inducible;NAD(P)H quinone dehydrogenase 1;NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1;NAD(P)H:menadione oxidoreductase 1;NAD(P)H:Quinone acceptor oxidoreductase type 1;NAD(P)H:quinone oxidoreductase 1;NAD(P)H:quinone oxireductase;NMOR 1;NMOR I;NQO 1;Phylloquinone reductase;QR 1;Quinone reductase 1

Research Areas:Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11B3

UNIProt ID:P15559

Accession:

Background:This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human NQO1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:1000-1:5000

Calculated MW:31 kDa

ObservedMW:31 kDa