Recombinant NOX2 Monoclonal Antibody

SKU: AN301105L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:NOX2

Target Synonym:IMD;NOX;GP91;AMCBX;AMCBX2;CGD;GP91-1;GP91-PHOX;GP91PHOX;IMD34;NOX2;p91-PHOX;CYBB;beta polypeptide;CGD91-phox;CY24B;Cytochrome b 245;Cytochrome b(558) beta chain;Cytochrome b(558) subunit beta;Cytochrome b-245 heavy chain;Cytochrome b558 subunit beta;GP91 PHOX;Heme-binding membrane glycoprotein gp91phox;NADPH oxidase 2;Neutrophil cytochrome b 91 kDa polypeptide;p22 phagocyte B-cytochrome;P91 PHOX;Superoxide-generating NADPH oxidase heavy chain subunit;gp91-phox

Research Areas:Immunology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:10F9

UNIProt ID:P04839

Accession:

Background:Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human NOX2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-5000;

Calculated MW:65 kDa

ObservedMW:65 kDa