Recombinant Myosin Light Chain 3 Monoclonal Antibody

SKU: AN301607L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Myosin Light Chain 3

Target Synonym:Myl;MYL3;alkali;Cardiac myosin light chain 1;CMH8;CMLC1;ELC of myosin;Essential light chain of myosin;light chain 1;light chain 3;light polypeptide 3;MLC1SB;MLC1V;Myosin;Myosin light chain 1;Myosin light chain 1 slow;Myosin light chain 1 slow twitch muscle B/ventricular isoform;Myosin light chain 3;OTTHUMP00000165922;skeletal;slow;Slow skeletal ventricular myosin alkali light chain 3;slow-twitch muscle B/ventricular isoform;ventricular;Ventricular/slow twitch myosin alkali light chain;VLC1

Research Areas:Signal Transduction;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A310

UNIProt ID:P08590

Accession:

Background:MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury.

Concentration:1 mg/mL

Immunogen:Recombinant human Myosin Light Chain 3 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000;FCM 1:50-1:100

Calculated MW:22 kDa

ObservedMW:22 kDa