Recombinant Mouse MCP-3/CCL7 protein

SKU: CD00307

Size:2 ug

Background:Mouse CCL7, also known as MARC, is belonging to the CC chemokine family. It is encoded by the gene CCL7 and was isolated from a mouse mast cell line after Fc epsilon RI triggering by IgE plus antigen. Sequence comparisons suggest that MARC may be the mouse homologue of the human MCP-3 gene. Similar to the human system, MARC/FIC is postulated the Mouse MCP-3. The MCP-3 protein family signals through CCR2 expect MCP-1 and possess cross-reacts across species. CCL7/MCP3 has chemotactic fuction for monocytes and eosinophils, but not for neutrophils.

Research_area:Immunology

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Monocyte Chemotactic Protein-3/CCL7

Biological activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1-3 ng/ml.

Synonyms:MCP-3/CCL7, ABCD-, Abcd-2, Scya, Scya17, Scya17l, TA, Tarc,Mouse

Endotoxin:Less than 1 EU/μg of rMuMCP-3/CCL7 as determined by LAL method.

Storage:-20ºC

Sequence:QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP

uniprot accession:Q3366

Molecular weight:Approximately 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2× PBS, pH 7.4.