Recombinant Mouse FLT3LG Protein(His Tag)

SKU: PDMM100222

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:FLT3LG

Target Synonym:TNFSF;APT1LG;Apo I Ligand;APT1LG1;APTL;CD178;CD95L;Fas-Lg;FL;Flt3 ligand;Flt3-L;FLT3-LG;Fms-Related Tyrosine Kinase 3 ligand;Fms-related tyrosine kinase 3 ligand (Flt3L);gld;SL cytokine;soluble Fas Ligand (sFasL);Tnfs;TNFSF6;Tnlg1a;Flt3lg;Flt3L;Flt3 ligand

Research Areas:Immunology;Stem cells;Signal Transduction;Developmental Biology

Conjugation:

Target Species:Mouse

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:P49772

Accession:P49772

Background:FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

Concentration:

Activity:Not validated for activity

Sequence:Gly27-Gln189

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method

Calculated MW:17.8 kDa

ObservedMW:28-35 kDa