Recombinant Mouse Chromogranin-A/Chga protein (His Tag)

SKU: PDEM100227

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Chromogranin-A;Chga

Target Synonym:CHG A;CMGA;CgA;Chga;Chromogranin A;Chromogranin A parathyroid secretory protein 1;Chromogranin A precursor;ChromograninA;ER-37;Pancreastatin;Parastatin;Parathyroid secr;beta Granin;betagranin (N-terminal fragment of chromogranin A);catestatin;chromofungin

Research Areas:

Conjugation:

Target Species:Mouse

Expression Host:E.coli

Application:Immunogen

Fusion tag:N-His

UNIProt ID:P26339

Accession:P26339

Background:Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation . Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress .

Concentration:

Activity:Not validated for activity

Sequence:Leu19-Met150

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:14.4 KDa

ObservedMW:15-20 kDa