Recombinant Mouse Ceacam1 Protein(His Tag)

SKU: PDMM100233

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Ceacam1

Target Synonym:Antigen CD;meconium antigen;Biliary glycoprotein;Carcinoembryonic antigen-related cell adhesion molecule;MHVR;CEACAM;Antigen CD66;BGP 1;Biliary glycoprotein 1;Biliary glycoprotein D;Carcinoembryonic antigen-related cell adhesion molecule 1;CD66a;meconium antigen 100;MHV-R;MHVR1;Murine hepatitis virus receptor;Bgp;Bgp1;Ceacam1;CEACAM-1;CEACAM-2;BGP;CEA-1;bb-1;BGP-1;BGPI;Biliary glycoprotein adhesion molecule;Carcinoembryonic antigen related cell adhesion molecule 1;carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein);Cc1;C-CAM;CD66a antigen;Cea1;Cea-1;Cea7;Cea-7;CEAM1;Hv2;Hv-2;mCEA1;Mhv-1;mmCGM1;mmCGM1a;mmCGM2

Research Areas:Cancer;Immunology;Microbiology;Cell Biology

Conjugation:

Target Species:Mouse

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:P31809

Accession:P31809

Background:The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

Concentration:

Activity:Not validated for activity

Sequence:Glu35-Gly428

Purity:> 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method

Calculated MW:43.2 kDa

ObservedMW:55-80 kDa