Recombinant MCM7 Monoclonal Antibody

SKU: AN302062L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:MCM7

Target Synonym:CDC;PNAS;P1CDC;PPP1R;P1.1-MCM;MCM;MCM7;CDC47;MCM2;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104;formerly;homolog of;regulatory subunit 104;S. cerevisiae;CDABP0042;CDC 47;CDC47 homolog;DNA replication licensing factor MCM7;Homolog of S. cerevisiae Cdc47;MCM 2;MCM 7;MCM7 minichromosome maintenance deficient 7;MCM7_HUMAN;Minichromosome maintainence;Minichromosome Maintainence 7;Minichromosome maintenance complex component 7;Minichromosome maintenance deficient 7;Minichromosome maintenance protein 7;P1.1 MCM3;PNAS 146;Protein phosphatase 1

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IF;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A782

UNIProt ID:P33993

Accession:

Background:The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:20000-1:50000;IF 1:100;IP 1:50-1:100

Calculated MW:81 kDa

ObservedMW:81 kDa