Recombinant Human SEMA3A Protein(Fc Tag)

SKU: PDMH100251

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:SEMA3A

Target Synonym:SEMA3A;COLL1;HH16;Hsema-I;Hsema-III;SEMA1;SEMAD;SEMAIII;SEMAL;SemD;coll-1

Research Areas:Cancer;Cardiovascular;Neuroscience

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:Q14563

Accession:Q14563

Background:This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with an schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with an the progression of Alzheimer's disease.

Concentration:

Activity:Not validated for activity

Sequence:Lys26-Phe546

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:82.2 kDa

ObservedMW:80-90 kDa