Recombinant Human PPIH Protein (His Tag)

SKU: PKSH032879

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: PPIH

Target Synonym: CYP20;CYPH;CypH;PPIH;PPIase H;Peptidyl-Prolyl Cis-Trans Isomerase H;Rotamase H;Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H;U-snRNP-Associated Cyclophilin SnuCyp-20;USA-CYP

Research Areas: Signal Transduction;epigenetics and nuclear signal;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: O43447

Accession: O43447

Background: Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Met 177

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 21.4 kDa

ObservedMW: 24 kDa