Recombinant Human PPAR-delta protein (His tag)

SKU: PDEH100816

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:PPAR-delta

Target Synonym:NR1C2;NUC1;NUCI;Nuclear hormone receptor 1;Nuclear receptor subfamily 1 group C member 2;PPAR-beta;PPAR-delta;PPARB;Peroxisome proliferator-activated receptor beta;Peroxisome proliferator-activated receptor delta

Research Areas:epigenetics and nuclear signal

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-His

UNIProt ID:Q03181

Accession:Q03181

Background:Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues.Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand

Concentration:

Activity:Not validated for activity

Sequence:Leu260-Glu426

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:18.3 kDa

ObservedMW:20 kDa