Recombinant Human Peroxiredoxin-3/PRDX3 Protein

SKU: PKSH032882

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Peroxiredoxin-3;PRDX3

Target Synonym: AOP-1;AOP1;Antioxidant Protein 1;HBC189;PRDX3;Peroxiredoxin III;Peroxiredoxin-3;Protein MER5 homolog;Prx-III;Thioredoxin-Dependent Peroxide Reductase Mitochondrial

Research Areas: Signal Transduction;Cell biology;Cardiovascular;Neuroscience;Cancer;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: P30048

Accession: P30048

Background: Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Concentration:

Activity: Not validated for activity

Sequence: Pro63-Gln256

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 21.6 kDa

ObservedMW: 25 kDa