Recombinant Human MAP1D Protein (His Tag)

SKU: PKSH032749

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: MAP1D

Target Synonym: MAP 1D;MAP1D;METAP1D;MetAP 1D;Metap1l;Methionine Aminopeptidase 1D Mitochondrial;Methionyl Aminopeptidase Type 1D Mitochondrial

Research Areas: Signal Transduction;epigenetics and nuclear signal;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His & C-His

UNIProt ID: Q6UB28

Accession: Q6UB28

Background: Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.

Concentration:

Activity: Not validated for activity

Sequence: Arg44-Ala335

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 35.4 kDa

ObservedMW: 35-40 kDa