Recombinant Human IL-7 Receptor Subunit alpha/IL-7RA/CD127 (C-6His)

SKU: PKSH033944

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: IL-7RA;CD127

Target Synonym: CDW;IL7R;CD127;CDW127;IL-7R-alpha;IL7RA;ILRA;IL-7R;IL-7RA;IL-7Rα;Interleukin-7 receptor subunit alpha; IL-7RαCD 127;CD127 antigen;IL 7R;IL 7R alpha;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL7Ralpha;Interleukin 7 receptor;Interleukin 7 receptor alpha chain;Interleukin 7 receptor isoform H5 6

Research Areas: immunology;Stem cells

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P16871

Accession: P16871

Background: Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

Concentration:

Activity: Not validated for activity

Sequence: Glu21-Gly236

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 25.7 kDa

ObservedMW: 40-55 kDa