Recombinant Human GLP1R Protein (Fc Tag)

SKU: PKSH033669

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: GLP1R

Target Synonym: GLP-1 receptor;GLP-1-R;Glucagon-like peptide 1 receptor

Research Areas: Cardiovascular;Neuroscience;metabolism

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID: P43220

Accession: P43220

Background: GLP1R Belongs to the G-protein coupled receptor 2 family that is synthesized as a 172 amino acid (aa). GLP1R is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It may form homodimers and heterodimers with GIPR. GLP1R is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Concentration:

Activity: Not validated for activity

Sequence: Arg24-Tyr145

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 41.2 kDa

ObservedMW: 50-75 kDa