Recombinant Human Galectin-1 protein

SKU: CD01752

Size:10 ug

Background:Human Galectin-1 also named BHL, Galaptin, GBP, L- 14 and LGALS1, is belonging to the galectins family and it is encoded by the LGALS1 gene in human. Galectin-1 is expressed by the endometrial stromal cells throughout the menstrual cycle. Galectin-1 contains a single carbohydrate recognition domain through which it can bind glycans both as a monomer and as a homodimer. Dimers are non-covenantly bound and will spontaneou sly disassociate in low concentration. Galectin -1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin - 1 is thought to play a role in the immunosuppression required for a successful pregnancy. Human Galectin-1 shares 88 %-90 % amino acid sequence identity with rat and mouse.

Research_area:Others

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Galectin-1 (rHuGalectin-1)

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.-1 ng/ml.

Synonyms:Galectin-1,LGALS1, GAL1, GBP,Human

Endotoxin:Less than 0.1 EU/ μg of rHuGalectin -1 as determined by LAL method.

Storage:-20ºC

Sequence:ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD

uniprot accession:P9382

Molecular weight:Approximately 14.6 kDa, a single non-glycosylated polypeptide chain containing 134 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μ m filtered solution in PBS,pH 7.4，with 1 mM DTT.