Recombinant Human EphB2 Protein (Fc Tag)

SKU: PKSH032012

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: EphB2

Target Synonym: CAPB;DRT;EK5;EPHB2;EPHT3;ERK;Ephrin type-B receptor 2;Hek5;PCBC;Tyro5

Research Areas: Cardiovascular,Neuroscience,Signal Transduction,Stem Cells,Cancer

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID: P29323

Accession: Q6NVW1

Background: Ephrin type-B receptor 2(EPHB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHB2 contains 1 Eph LBD domain; 2 fibronectin type-III domains; 1 protein kinase domain and 1 SAM domain. Ephrin receptors and their ligands; the ephrins; mediate numerous developmental processes; particularly in the nervous system. Based on their structures and sequence relationships; ephrins are divided into the ephrin-A (EFNA) class; which are anchored to the membrane by a glycosylphosphatidylinositol linkage; and the ephrin-B (EFNB) class; which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

Concentration:

Activity: Not validated for activity

Sequence: Val19-Ser482

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 78.5 kDa

ObservedMW: 95-120 kDa