Recombinant Human Clusterin/ApoJ Protein (aa 23-449, His Tag)

SKU: PKSH032260

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Clusterin;ApoJ

Target Synonym: AAG4;APO-J;APOJ;Aging-Associated Gene 4 Protein;Apo-J;Apolipoprotein J;CLI;CLU;CLU1;CLU2;Clusterin;Complement Cytolysis Inhibitor;Complement-Associated Protein SP-40;KUB1;Ku70-Binding Protein 1;NA1/NA2;TRPM-2;Testosterone-Repressed Prostate Message 2

Research Areas: Signal Transduction;Cardiovascular;Cancer;immunology;metabolism;

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P10909

Accession: P10909

Background: Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis; heart; ovary; adrenal gland; brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death; tumor progression; and neurodegenerative disorders. In addition;Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer; organ regeneration; infection; Alzheimer disease; retinitis pigmentosa; myocardial infarction; renal tubular damage; autoimmunity and others.

Concentration:

Activity: Not validated for activity

Sequence: Asp23-Glu449

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 51.1 kDa

ObservedMW: 28-40 kDa