Recombinant Human CDH11 (C-6His)

SKU: EPT231

Size:10ug

Description:Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a 6His tag at the C-terminus.

Accession:Q96CZ9

Molecular weight:66.63 KDa

Apparent molecular weight:82 KDa, reducing conditions

Other names:Cadherin 11 Type 2 OB-cadherin (Osteoblast); Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c; CDH11

Storage condition:Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Purity:Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin:Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Biological activity:

Redissolve:Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Storage:Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Delivery condition:The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Background:Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.