Recombinant Human CD74 protein (His Tag)

SKU: PDEH100704

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:CD74

Target Synonym:CD 74;CD74 antigen (invariant polypeptide of major histocompatibility complex;CD74 molecule;CLIP;DHLAG;Gamma chain of class II antigens;HG2A;HLA class II histocompatibi;class II antigen-associated);class II invariant chain;major histocompatibility complex

Research Areas:immunology

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:Immunogen

Fusion tag:N-His

UNIProt ID:P04233

Accession:P04233

Background:Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Concentration:

Activity:Not validated for activity

Sequence:Gln73-Met296

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:26.6 kDa

ObservedMW:30-33 kDa