Recombinant Human Cadherin-11/CDH11 Protein (Fc & His Tag)

SKU: PKSH032137

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Cadherin-11;CDH11

Target Synonym: CDH11;Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c;Cadherin 11 Type 2 OB-cadherin (Osteoblast)

Research Areas:

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc-His

UNIProt ID: Q96CZ9

Accession: Q96CZ9

Background: Cadherin-11; also known as OSF-4; Osteoblast cadherin and CDH11; is a type II classical cadherin from the cadherin superfamily; integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells; may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small; highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

Concentration:

Activity: Not validated for activity

Sequence: Phe23-Thr617

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 93.6 kDa

ObservedMW: 110 kDa