Recombinant Human AKR1C2 Protein

SKU: PKSH032054

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: AKR1C2

Target Synonym: 2-Dihydrobenzene-1;2-Diol Dehydrogenase;3-Alpha-HSD3;Aldo-Keto Reductase Family 1 Member C2;Chlordecone Reductase Homolog HAKRD;DD-2;DD/BABP;DD2;Dihydrodiol Dehydrogenase 2;Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein;Trans-1;Type III 3-Alpha-Hydro

Research Areas: Signal Transduction;Cancer;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: P52895

Accession: P52895

Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Tyr323

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 36.7 kDa

ObservedMW: 35 kDa