Recombinant HNMT Monoclonal Antibody

SKU: AN300161P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:HNMT

Target Synonym:MRT;HNMT;HMT;HNMT-S1;HNMT-S2;MRT51

Research Areas:Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IP

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:2D5

UNIProt ID:P50135

Accession:

Background:In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human HNMT protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;IP 0.5-2 μL/mg of lysate

Calculated MW:33 kDa

ObservedMW:33 kDa