Recombinant Histone H4 (CT) Monoclonal Antibody

SKU: AN301940L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Histone H4

Target Synonym:H4F;methyl histone H;methylated histone H;HIST2H;HIST1H;HISTH4H;histone H;HIST2H4B;H4/o;histone H4;HIST1H4A;FO108;H4/p;HIST1H4;Hist4h4;HISTH4H4;methyl histone H4;methylated histone H4;H4/A;H4FA;H4/I;H4FI;HIST1H4B;H4/G;H4FG;HIST1H4C;H4/B;H4FB;HIST1H4D;H4/J;H4FJ;HIST1H4E;H4/C;H4FC;HIST1H4F;H4/H;H4FH;HIST1H4H;H4/M;H4FM;HIST1H4I;H4/E;H4FE;H4/D;H4FD;HIST1H4K;H4/K;H4FK;HIST1H4L;H4/N;H4F2;H4FN;HIST2H4;HIST2H4A;H4;H4C1;H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4C11;H4C12;H4C13;H4C14;H4C15;H4-16;A;I;H4B;H4J;H4H;H4M;H4E;HIST1H4J;H4D;H4C;H4/p;histone H4;HIST1H4B H4/I

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse;Yeast;Pig

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A656

UNIProt ID:P62805

Accession:

Background:Histones are a family of basic proteins that form the core of the nucleosome – the fundamental structural unit of chromatin. In a single nucleosome, core histone proteins H2A, H2B, H3, and H4 form an octamer around which the DNA is tightly wrapped. Histone proteins not only serve to compact chromosomal DNA but also play vital roles in the dynamic and long-term regulation of genes by a wide variety of post-translational modifications (PTMs). These PTMs including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone H4 is primarily acetylated at Lys5, 8, 12, and 16, and methylated at Lys20.

Concentration:1 mg/mL

Immunogen:Synthetic peptide corresponding to the C-terminus of human histone H4 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:2000-1:10000;IHC 1:50-1:100

Calculated MW:11 kDa

ObservedMW:11 kDa