Recombinant FOXC1 Monoclonal Antibody

SKU: AN301947L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:FOXC1

Target Synonym:IHG;FOXC;ASGD;FKHL;IRID;RIEG;FOXC1;ARA;ASGD3;FKHL7;FREAC-3;FREAC3;IGDA;IHG1;IRID1;RIEG3;FKH L7;FKHL 7;Forkhead (Drosophila) like 7;Forkhead box C1;Forkhead box protein C1;Forkhead drosophila homolog like 7;Forkhead like 7;Forkhead related activator 3;Forkhead related protein FKHL7;Forkhead related transcription factor 3;Forkhead-related protein FKHL7;Forkhead-related transcription factor 3;FOX C1;FOXC 1;FREAC 3;IHG 1;IRID 1;Iridogoniodysgenesis type 1;Myeloid factor delta

Research Areas:Epigenetics and Nuclear Signaling;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A663

UNIProt ID:Q12948

Accession:

Background:FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Research studies have shown that alterations in FoxC1 expression are linked to breast cancer invasiveness and have been shown to modulate proliferation and migration of breast cancer cells in vitro.

Concentration:1 mg/mL

Immunogen:Recombinant human FOXC1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:70-74 kDa

ObservedMW:70 kDa