Recombinant FBX32 Monoclonal Antibody

SKU: AN301124L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:FBX32

Target Synonym:FBX;FBXO;FBXO32;Fbx32;MAFbx;4833442G10Rik;AI430017;Atrogin 1;ATROGIN1;Atrogin-1;Atrophy gene 1;F box only protein 32;F-box only protein 32;F-box protein 32;fbxo25;FLJ32424;MGC108443;MGC137646;MGC33610;Muscle atrophy F box;Muscle atrophy F box protein;Muscle atrophy F-box protein;FBX32

Research Areas:Cell Biology;Stem Cells;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:12G7

UNIProt ID:Q969P5

Accession:

Background:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human FBX32 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:42 kDa

ObservedMW:42 kDa