Recombinant FAK Monoclonal Antibody

SKU: AN301036L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:FAK

Target Synonym:PTK;PPP1R;FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;PTK2;FADK 1;FAK related non kinase polypeptide;Focal adhesion Kinase;Focal adhesion kinase 1;Focal adhesion kinase isoform FAK Del33;Focal adhesion kinase related nonkinase;Protein phosphatase 1 regulatory subunit 71;Protein tyrosine kinase 2;Protein-tyrosine kinase 2;PTK2 protein tyrosine kinase 2

Research Areas:Cardiovascular;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5A11

UNIProt ID:Q05397

Accession:

Background:PTK2(protein tyrosine kinase 2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human FAK protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:400-1:1000;WB 1:1000-1:5000

Calculated MW:119 kDa

ObservedMW:119 kDa