Recombinant Ephrin-A1/EFNA1 Monoclonal Antibody

SKU: AN300352P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:EFNA1

Target Synonym:EPLG;TNF Alpha-Induced Protein;Immediate Early Response Protein B;EPH-Related Receptor Tyrosine Kinase Ligand;Tumor Necrosis Factor Alpha-Induced Protein;EFNA;TNFAIP;Ephrin-A;EPH-Related Receptor Tyrosine Kinase Ligand 1;Ephrin-A1;Immediate Early Response Protein B61;LERK-1;TNF Alpha-Induced Protein 4;Tumor Necrosis Factor Alpha-Induced Protein 4;EPLG1;LERK1;TNFAIP4;EFNA1;B61;ECKLG;EFL 1;EFL1;EFNA 1;EPH related receptor tyrosine kinase ligand 1;Ephrin A1;EphrinA1;EPLG 1;LERK 1;Ligand of eph related kinase 1;OTTHUMP00000033242;OTTHUMP00000033271;secreted form;TNFAIP 4;Tumor necrosis factor alpha induced protein 4

Research Areas:Cardiovascular;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P

Isotype:IgG

Clonality:Monoclonal

Clone NO.:10F14

UNIProt ID:P20827

Accession:

Background:EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization.

Concentration:1 mg/mL

Immunogen:Recombinant Human Ephrin-A1/EFNA1 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500

Calculated MW:

ObservedMW: