Recombinant EGFR Monoclonal Antibody

SKU: AN300843L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:EGFR

Target Synonym:PIG;HER;Proto-oncogene c-ErbB;Receptortyrosine-protein kinase erbB;Receptor tyrosine-protein kinase erbB;NISBD;EGFR;ERBB;ERBB1;HER1;NISBD2;PIG61;mENA;ErbB-1;Receptortyrosine-protein kinase erbB-1;Epidermal growth factor receptor;Proto-oncogene c-ErbB-1;Receptor tyrosine-protein kinase erbB-1; NISBD2;epidermal growth factor receptor;ERBB;ERBB1;HER1;mENA;NISBD2;PIG61;Avian erythroblastic leukemia viral (v erb b) oncogene homolog;Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog);Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian);ErbB1;ERBB;erb-b2 receptor tyrosine kinase 1;Errp;Oncogen ERBB;Receptor tyrosine protein kinase ErbB 1;SA7;Species antigen 7;Urogastrone;v-erb-b Avian erythroblastic leukemia viral oncogen homolog;wa2;Wa5

Research Areas:Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5H2

UNIProt ID:P00533

Accession:

Background:The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human EGFR protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:2000-1:10000

Calculated MW:134 kDa

ObservedMW:175 kDa