Recombinant DPP4/CD26 Monoclonal Antibody

SKU: AN301964L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:DPP4/CD26

Target Synonym:DPP;dipeptidylpeptidase;dipeptidyl-peptidase;dipeptidyl peptidase;T-cell activation antigen CD;adenosine deaminase complexing protein;DPP4;ADABP;ADCP2;CD26;DPPIV;TP103;Dipeptidyl peptidase IV;ADCP-2;dipeptidyl-peptidase 4;dipeptidyl peptidase 4;DPP IV;dipeptidylpeptidase 4;T-cell activation antigen CD26;adenosine deaminase complexing protein 2;dipeptidylpeptidase IV;Dipeptidyl peptidase IV (DPP IV);ADABP Protein;ADCP2 Protein;CD26 Protein;DPPIV Protein;Human;TP103 Protein

Research Areas:Immunology;Cell Biology;Stem Cells;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A680

UNIProt ID:P27487

Accession:

Background:DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding domain are located in the extracellular fragment. DPP4/CD26 is a multifunctional protein that exists in both a membrane bound form as well as an extracellular soluble form. As a peptidase, it removes N-terminal dipeptides sequentially from proteins with a proline or alanine as the penultimate P1 amino acid. DPP4/CD26 has been shown to cleave a wide range of substrates including GLP-1, BNP, etc. In addition to its peptidase activity, DPP4/CD26 interacts with multiple important cell surface ligands, such as adenosine deaminase, fibronectin, and IGF2 receptor to influence processes like T cell activation, cell migration and proliferation.

Concentration:1 mg/mL

Immunogen:Recombinant human DPP4/CD26 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:500

Calculated MW:110 kDa

ObservedMW:110 kDa