Recombinant Cynomolgus OX40/TNFRSF4 Protein (His Tag)

SKU: PKSQ050014

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Immune Checkpoint Proteins

Abbreviation: OX40;TNFRSF4

Target Synonym: Lck/Yes-related novel protein tyrosine kinase;Tyrosine-protein kinase Lyn (LYN);V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;p53Lyn;p56Lyn and JTK8

Research Areas: Signal Transduction;

Conjugation:

Target Species: Cynomolgus macaques

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P07948

Accession: XM_005545122.1

Background: LYN contains one protein kinase domain, one SH2 domain, one SH3 domain, and the protein kinase domain plays an important role in its localization in the cell membrane. LYN is also thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. In addition, LYN is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).

Concentration:

Activity: Not validated for activity

Sequence: Lys28-Ala214

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 21.3 kDa

ObservedMW: 35-50 kDa