Recombinant CD8 α Monoclonal Antibody

SKU: AN301083L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CD8 α

Target Synonym:Leu;T-lymphocyte differentiation antigen T8/Leu;CD8A;CD8;Leu2;MAL;p32;T8;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD8;Leu-2;Ly-2;alpha polypeptide (p32);CD8 antigen alpha polypeptide;CD8 antigen alpha polypeptide (p32);CD8A antigen;CD8A molecule;Leu2 T lymphocyte antigen;Ly3;LYT3;OKT8 T cell antigen;OTTHUMP00000160760;OTTHUMP00000160764;OTTHUMP00000203528;OTTHUMP00000203721;T cell antigen Leu2;T cell co receptor;T8 T cell antigen;T8/Leu-2 T-lymphocyte differentiation antigen;CD8

Research Areas:Immunology;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:2C9

UNIProt ID:P01732

Accession:

Background:The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human CD8 α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1000;WB 1:1000-5000

Calculated MW:26 kDa

ObservedMW:35 kDa